PEA (PALMITOYLETHANOLAMIDE) 400mg x 90 Capsules
We stock this product as it is something we ourselves have used very successfully with our own elderly dogs, for joint pain, alongside their standard regime.
Breakthrough Natural Support for:
- Itching caused by sensitivity to environmental allergens
- Joint Relief
- Cognitive Health
- Micronised for optimum potency
- Only form formulated specifically for animals to ensure maximum benefits
- No Fillers, No Binders No Glues or Chemical additives of any kind
This supplement is human food grade quality and has been carefully formulated to meet the correct dosage needs for our pets. Dr Vince MacNally has more than 40 years clinical experience as a vet, and is a strong advocate for using holistic means where possible. PEA has many applications including
- Itchy Skin Support
- Joint Support
- Cognitive health support
- Pain management
PEA Fact Sheet
1. What is PEA?
- Palmitoylethanolamide (PEA) is a fatty acid amide, naturally produced in the body.
- It plays a significant role in modulating pain and inflammation.
2. Source
- Synthesised from cell membrane phospholipids by an enzyme (N-acyl phosphatidylethanolamine phospholipase D).
- Related to anandamide – a cannabinoid neurotransmitter occurring in the body, which influences many physiological functions.
- Produced by many different organs, including the brain, liver, muscle, fat tissue, intestinal tract, skin and immune cells (mast cells and macrophages).
- Formed “on demand” in response to physiological needs (inflammation, pain, immune challenges, cellular injury and stress).
3. Mechanism of Action
- Regulates inflammation and analgesia (pain relief) by activating the PPAR-α receptor (peroxisome proliferator-activated receptor alpha) which is widely distributed in tissues and cells throughout the body.
- Interacts with cannabinoid receptors (CB1 and CB2) contributing to neuroprotective and anti-inflammatory properties.
4. Dietary PEA
- Found in various foods such as soy lecithin, soybeans, egg yolk, peanuts, and alfalfa.
- Natural form is poorly water-soluble however, hence the importance of micronisation to enhance bioavailability.
5. Safety and Tolerance
- Well-tolerated and safe, even at high doses.
6. Uses
In clinical studies PEA has been shown to help:
7. Why Supplement with PEA?
Although palmitoylethanolamide is formed naturally in the body, when chronic inflammation or pain is present, the demand for PEA can exceed the body’s ability to produce it.
And when this occurs, the lack of sufficient PEA leaves the body unable to control the signs of various conditions such as atopic dermatitis or osteoarthritis, for example.
Supplementation in these circumstances, provides additional PEA to support the body’s anti-inflammatory and pain relieving mechanisms, leading to an improvement in well-being.
8. The importance of micronisation
Reducing the particle size of PEA (micronisation), without altering chemical structure, significantly enhances its bioavailability, absorption by the body, efficacy and safety.
This is important in ensuring that palmitoylethanolamide delivers maximum health benefits, and is why Vince the Vet PEA is micronised.
9. Purity is key
Ensuring the end product contains only 100% natural palmitoylethanolamide, and nothing else at all, is critical for safety, efficacy and optimum potency.
This means using only the highest quality raw materials available, and excluding fillers, binders, glues and chemical additives of any kind.
It’s also vital that the Certificate of Analysis confirms that heavy metal and microbe readings are well below acceptable levels, as is the case for Vince the Vet PEA:
Directions for Use
Add to the diet daily in accordance with the guidelines on the labels.
Cats
Half a capsule daily.
After the first 12 weeks, the dose can be halved to see if this is sufficient for maintenance.
Dogs
Small (5kg – 10kg): Half a capsule twice daily
(this can easily be opened and the powder mixed into a little tasty food).
Medium (11kg – 25kg): One capsule twice daily.
Large (26kg – 35kg plus): Two capsules twice daily.
After the first 12 weeks, the dose can be halved to see if this is sufficient for maintenance.
Horses
3 capsules twice daily.
After the first 12 weeks, the dose can be halved to see if this is sufficient for maintenance.
Ingredients
Palmitoylethanolamide (plant origin).
Each capsule (Hydroxypropyl methylcellulose) typically contains 400mg.
Analysis
Crude protein: 0%;
Crude fibres: 0%;
Crude oils and fats: 100%;
Crude ash: 0%
